The carpal tunnel is a narrow passageway found on the anterior portion of the wrist. It serves as the entrance to the palm for several tendons and the median nerve. In this article, we will look at the borders and contents of the carpal tunnel and its clinical significance. Pro Feature - 3D Model You've Discovered a Pro Feature Access our 3D Model Library Explore, cut, dissect, annotate and manipulate our 3D models to visualise anatomy in a dynamic, interactive way. Learn More Borders The carpal tunnel is formed by two layers: a deep carpal arch and a superficial flexor retinaculum. The deep carpal arch forms a concave surface, which is converted into a tunnel by the overlying flexor retinaculum (transverse carpal ligament). Carpal Arch Concave on the palmar side, forming the base and sides of the carpal tunnel. Formed laterally by the scaphoid and trapezium tubercles Formed medially by the hook of the hamate and the pisiform Flexor Retinaculum Thick connective tissue which forms the roof of the carpal tunnel. Turns the carpal arch into the carpal tunnel by bridging the space between the medial and lateral parts of the arch. Spans between the hook of hamate and pisiform (medially) to the scaphoid and trapezium (laterally). To find where the carpal tunnel begins on yourself, locate your distal wrist crease, which aligns with the entrance of the carpal tunnel. By TeachMeSeries Ltd (2025) Fig 1Transverse section of the carpal tunnel. Contents The carpal tunnel contains a total of 9 tendons, surrounded by synovial sheaths, and the median nerve. The palmar cutaneous branch of the median nerve is given off prior to the carpal tunnel, travelling superficially to the flexor retinaculum. Tendons The tendon of flexor pollicis longus Four tendons of flexor digitorum profundus Four tendons of flexor digitorum superficialis The 8 tendons of the flexor digitorum profundus and flexor digitorum superficialis are surrounded by a single synovial sheath. The tendon of flexor pollicis longus is surrounded by its own synovial sheath. These sheaths allow free movement of the tendons. Sometimes you may hear that the carpal tunnel contains another tendon, the flexor carpi radialis tendon, but this is located within the flexor retinaculum and not within the carpal tunnel itself! By TeachMeSeries Ltd (2025) Fig 2The muscular and tendinous components of the carpal tunnel Median Nerve Once it passes through the carpal tunnel, the median nerve divides into 2 branches: the recurrent branch and palmar digital nerves. The palmar digital nerves give sensory innervation to the palmar skin and dorsal nail beds of the lateral three and a half digits. They also provide motor innervation to the lateral two lumbricals. The recurrent branch supplies the thenar muscle group. For a more detailed look at the median nerve, take a look here. Clinical Relevance Carpal Tunnel Syndrome Compression of the median nerve within the carpal tunnel can cause carpal tunnel syndrome (CTS). It is the most common mononeuropathy and can be caused by thickened ligaments and tendon sheaths. Its aetiology is, however, most often idiopathic. If left untreated, CTS can cause weakness and atrophy of the thenar muscles. Clinical features include numbness, tingling and pain in the distribution of the median nerve. The pain will usually radiate to the forearm. Symptoms are often associated with waking the patient from their sleep and being worse in the mornings. Tests for CTS can be performed during physical examination: Tapping the nerve in the carpal tunnel to elicit pain in median nerve distribution (Tinel’s Sign) Holding the wrist in flexion for 60 seconds to elicit numbness/pain in median nerve distribution (Phalen’s manoeuvre) Treatment involves the use of a splint, holding the wrist in dorsiflexion overnight to relieve symptoms. If this is unsuccessful, corticosteroid injections into the carpal tunnel can be used. In severe case, surgical decompression of the carpal tunnel may be required. By TeachMeSeries Ltd (2025) Fig 3Thenar muscle wasting, secondary to carpal tunnel syndrome. Do you think you’re ready? Take the quiz below Pro Feature - Quiz The Carpal Tunnel Question 1 of 3 Submitting... Skip Next Rate question: You scored 0% Skipped: 0/3 1800 More Questions Available Upgrade to TeachMeAnatomy Pro Challenge yourself with over 1800 multiple-choice questions to reinforce learning Learn More Print Article Rate This Article