The Axilla Region - Podcast Version TeachMeAnatomy 0:00 / 0:00 1x 0.25x 0.5x 0.75x 1x 1.25x 1.5x 1.75x 2x The axilla is a pyramidal region located inferior to the glenohumeral joint and shoulder girdle, at the junction of the upper limb and thoracic wall. It acts as a passageway by which neurovascular and muscular structures enter and leave the upper limb. In this article, we shall examine the anatomy of the axilla – the borders, contents, and any clinical correlations. By TeachMeSeries Ltd (2026) Fig 1Anterior view of the right axilla region. Note the pyramidal shape, with 6 borders (or sides). Pro Feature - 3D Model You've Discovered a Pro Feature Access our 3D Model Library Explore, cut, dissect, annotate and manipulate our 3D models to visualise anatomy in a dynamic, interactive way. Learn More Borders The overall 3D shape of the axilla looks slightly like a pyramid. It consists of four walls, an apex, and a base: Apex (axillary inlet) – it is bounded by the clavicle anteriorly, the first rib medially, and the superior border of the scapula posteriorly. Lateral wall – formed by the intertubercular groove of the humerus, coracobrachialis muscle and short head of biceps brachii. Medial wall – consists of the serratus anterior and the thoracic wall (ribs and intercostal muscles). Anterior wall – contains the pectoralis major and the underlying pectoralis minor and the subclavius muscles. Posterior wall – formed by the subscapularis, teres major and latissimus dorsi. The size and shape of the axilla varies with arm position. Overhead abduction can contribute to narrowing of neurovascular passageways in susceptible individuals, increasing the risk of compression. By TeachMeSeries Ltd (2026) Fig 2Transverse section of the axilla region. Pro Feature - Dissection Atlas The axillary artery and its branches. The pectoralis muscles have been divided and reflected back. The axillary artery and its branches. The pectoralis muscles have been divided and reflected back. You've Discovered a Pro Feature Access our Dissection Image Library Enhance your understanding with high-resolution dissection images showcasing real-life anatomy. Learn More Contents The contents of the axilla region include muscles, nerves, vessels, and lymphatics: Axillary artery – the main artery supplying the upper limb. It is commonly referred as having three parts; one medial to the pectoralis minor, one posterior to pectoralis minor, and one lateral to pectoralis minor. Axillary vein – the main vein draining the upper limb. It is formed by the brachial veins and basilic vein, and receives the cephalic vein as a major tributary. Brachial plexus – a network of spinal nerves (C5–T1) that gives rise to the peripheral nerves supplying the upper limb. Axillary lymph nodes – a group of lymph nodes that filter lymph drained from the upper limb, breast, and pectoral region. By TeachMeSeries Ltd (2026) Fig 3Contents of the axilla region. Passageways Exiting the Axilla There are three main routes by which structures leave the axilla. The main route of exit is immediately inferiorly and laterally, into the upper limb. The majority of contents of the axilla region leave by this method. Another pathway is via the quadrangular space. This is a gap in the posterior wall of the axilla, allowing access to the posterior arm and shoulder area. Structures passing through include the axillary nerve and posterior circumflex humeral artery (a branch of the axillary artery. The last passageway is the clavipectoral triangle, which is an opening in the anterior wall of the axilla. It is bounded by the pectoralis major, deltoid, and clavicle. The cephalic vein enters the axilla via this triangle. By TeachMeSeries Ltd (2026) Fig 4Boundaries and contents of the clavipectoral triangle By TeachMeSeries Ltd (2026) Fig 5Posterior view of the shoulder region, showing the quadrangular space. The subscapularis muscle lies anteriorly, and so cannot be seen. Clinical Relevance Thoracic Outlet Syndrome The apex of the axilla region is an opening between the clavicle, first rib and the scapula. In this apex, the vessels and nerves may become compressed between the bones – this is called thoracic outlet syndrome. Common causes of thoracic outlet syndrome include: Trauma – e.g. fractured clavicle. Repetitive movements – seen commonly in occupations that require lifting of the arms. Cervical rib – an extra rib which arises from the seventh cervical vertebra. It often presents with pain in the affected limb (the distribution of pain is dependent on which nerve is compressed), tingling, muscle weakness and discolouration. Lymph Node Biopsy Approximately 75% of lymph from the breast drains into the axilla lymph nodes, so can be biopsied if breast cancer is suspected. If breast cancer is confirmed, the axillary nodes may need to be removed to prevent the cancer spreading. This is known as axillary clearance. During this procedure, the long thoracic nerve may become damaged, resulting in winged scapula. Do you think you’re ready? Take the quiz below Pro Feature - Quiz The Axilla Region Question 1 of 3 Submitting... Skip Next Rate question: You scored 0% Skipped: 0/3 1800 More Questions Available Upgrade to TeachMeAnatomy Pro Challenge yourself with over 1800 multiple-choice questions to reinforce learning Learn More Rate This Article