The study of the nervous system is essential for understanding innervation patterns, motor and sensory function, and neurovascular relationships. Given the complexity of the nervous system, using a consistent method to learn the features of each nerve is beneficial. In this article, a five-part framework for describing nerves will be outlined – site, type of nerve, roots, course, and innervation. This structure can be applied to any peripheral nerve and forms the basis for effective anatomical learning. Department of Anatomy, University of East Anglia A 5-part framework for learning the anatomy of nerves Pro Feature - 3D Model You've Discovered a Pro Feature Access our 3D Model Library Explore, cut, dissect, annotate and manipulate our 3D models to visualise anatomy in a dynamic, interactive way. Learn More Site The site refers to the anatomical region in which the nerve is located. This provides context for the structures the nerve supplies and its relationship to other anatomical landmarks. Examples: The median nerve is a nerve of the upper limb. The femoral nerve is a nerve of the thigh. The sciatic nerve is a nerve of the posterior lower limb. Type of Nerve The type of nerve describes the kind of fibres the nerve carries, which may include motor, sensory, or autonomic components. This classification helps predict the function of the nerve. Examples: The median nerve carries motor and sensory fibres to the forearm and hand. The femoral nerve carries motor fibres to the anterior thigh and sensory fibres to the thigh and leg. The vagus nerve carries motor, sensory, and parasympathetic fibres to thoracic and abdominal organs. Roots The roots describe the spinal nerve roots that contribute to the formation of a peripheral nerve. Peripheral nerves arise from the spinal cord as ventral (motor) and dorsal (sensory) roots, which join to form a spinal nerve. These roots combine and reorganise within nerve plexuses to give rise to the major peripheral nerves of the body. Examples: The ulnar nerve contains fibres from the C8–T1 nerve roots. The median nerve contains fibres from the C5–T1 nerve roots. The femoral nerve contains fibres from the L2–L4 nerve roots. Course The course describes the route the nerve takes as it travels through the body. This includes its relationships with surrounding structures and any notable anatomical landmarks it passes. Example (ulnar nerve): Passes along the medial border of the humerus. Passes posterior to the medial epicondyle. Lies deep to the flexor carpi ulnaris in the forearm. Enters the palm via Guyon’s canal. Terminates as superficial and deep branches. Innervation The innervation describes the structures supplied by the nerve. This includes motor innervation to muscles, sensory innervation to skin and joints, and in some cases, autonomic innervation (such as sympathetic or parasympathetic fibres to glands, blood vessels, or internal organs). Examples: The ulnar nerve provides motor supply to intrinsic hand muscles and sensory supply to the medial 1.5 digits. The median nerve provides motor supply to most forearm flexors and thenar muscles, and sensory supply to the lateral 3.5 digits. The vagus nerve provides motor, sensory, and parasympathetic supply to thoracic and abdominal organs. Print Article Rate This Article