The Cervix

Written by Louisa Thompson

Last updated December 23, 2025
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The Cervix - Podcast Version

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The cervix is the lower portion of the uterus, forming the narrow canal that connects the vagina with the uterine cavity. Functioning as a gateway between the external and internal reproductive tracts, the cervix plays a vital role in reproductive health.

Although continuous with the uterus, the cervix is anatomically and histologically distinct and is therefore considered as a separate structure.

In this article, we will look at the anatomy of the cervix – its structure, neurovascular supply and clinical correlations.

Diagram illustrating the overview of the female reproductive tract, including the vagina, fallopian tubes, uterus, and cervix.

Fig 1
Overview of the female reproductive tract.


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Anatomical Structure

The cervix is comprised of two main regions—ectocervix and endocervical canal—and contains two openings: the external os and the internal os.

  • Ectocervix – the portion that projects into the vaginal lumen. It is lined by non-keratinised stratified squamous epithelium. The central opening, called the external os, leads into the endocervical canal.
  • Endocervix (endocervical canal) – the inner canal that extends from the external os to the internal os, where it opens into the uterine cavity. It is lined by mucus-secreting simple columnar epithelium.
Diagram of the ectocervix and endocervical canal, illustrating their openings.

Fig 2
The ectocervix, endocervical canal, and their openings.


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Functions

The cervix serves two main functions:

  • Sperm entry – permits the entry of sperm into the uterus, particularly during ovulation when cervical mucus becomes thinner and more receptive.
  • Barrier function – forms a physical and immunological barrier that helps maintain sterility in the uterus. This is achieved through tight cervical closure and thick mucus within the endocervical canal.
Ectocervix view via speculum with an arrow marking the external os.

Fig 3
The ectocervix, visible via a speculum inserted into the vagina. The external os is marked with an arrow.


Neurovascular Supply

Blood Supply

The cervix receives its arterial supply primarily from the uterine artery, with contributions from the vaginal artery. Both vessels are branches of the internal iliac artery.

Venous drainage is via the uterine venous plexus, which drains into the uterine veins and then into the internal iliac veins.

Innervation

The cervix recieves visceral sensory, sympathetic and parasympathetic innervation:

  • Visceral sensory – transmit pain, stretch, and inflammatory stimuli. These fibres travel via autonomic pathways rather than somatic nerves.
  • Sympathetic – fibres arising from T10–L2 via the hypogastric nerves contribute to visceral pain transmission and vascular tone.
  • Parasympathetic – fibres from S2–S4 via the pelvic splanchnic nerves contribute to secretory activity, reflex motor responses, and also carry visceral afferent input.

The cervix has minimal somatic sensory innervation compared with the vagina and vulva. However, pain fibres are present, and cervical instrumentation may be painful, with marked inter-individual variation.

Posterior view illustration of the arterial supply to the female reproductive tract, including the ovaries, vagina, fallopian tubes, uterus, cervix, and pelvic arteries.

Fig 4
Posterior view of the arterial supply to the female reproductive tract.

Lymphatic Drainage

Lymph from the cervix drains to the iliac, sacral, aortic, and inguinal lymph nodes.

Clinical Relevance

Cervical Insufficiency

Cervical insufficiency (also known as cervical incompetence) occurs when the cervix is unable to remain closed during pregnancy, leading to premature dilation and potential pregnancy loss.

This condition highlights the mechanical barrier role of the cervix, particularly the internal os.

Management options include cervical cerclage – where a surgical suture is placed around the cervix to maintain its closed state.

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