The Seminal Vesicles

Original Author: Matt Quinn
Last Updated: August 2, 2017
Revisions: 21

The seminal vesicles (also known as the vesicular or seminal glands) are a pair of glands found in the pelvis, which function to produce many of the constituent ingredients of semen. They ultimately provide around 70% of the total volume of semen.

In this article we will consider the anatomical relations, functions, neurovascular relations and clinical significance of the seminal vesicles.


Anatomical Position and Structure

Fig 1.0 - Anatomical position of the seminal vesicles in relation to the vas deferens and prostate.

Fig 1.0 – Anatomical position of the seminal vesicles in relation to the vas deferens and prostate.

The seminal glands are a pair of 5cm long tubular glands. They are located between the bladder fundus and the rectum (separated from the latter by the rectovesicle pouch). Their most important anatomical relation is with the vas deferens, which combine with the duct of the seminal vesicles to form the ejaculatory duct, which subsequently drains into the prostatic urethra.

Internally the gland has a honeycombed, lobulated structure with a mucosa lined by pseudostratified columnar epithelium. These columnar cells are highly influenced by testosterone, growing taller with higher levels, and are responsible for the production of seminal secretions.

Embryology

The Seminal glands, along with the Ejaculatory ducts, Epididymis and Ductus (vas) deferens, are derived from the mesonephric ducts, the precursor structure of male internal genitalia.

These structures can easily be remembered using the acronym SEED.


Function

The secretions of the seminal gland have a key role in the normal functioning of semen, making up 70% of its total volume. The secretions contain;

  • Alkaline fluid – neutralises the acidity of the male urethra and vagina in order to facilitate the survival of spermatazoa.
  • Fructose – provides an energy source for spermatozoa.
  • Prostaglandins – have a role in suppressing the female immune response to foreign semen.
  • Clotting factors – designed to keep semen in the female reproductive tract post-ejaculation.

The remaining volume of semen is made up of testicular spermatozoa, prostatic secretions and mucus from the bulbourethral gland.


Vasculature

The arteries to the seminal gland are derived from the inferior vesicle, internal pudendal and middle rectal arteries, all of which stem from the internal iliac artery.


Innervation

The innervation of the gland, like much of the male internal genitalia, is sympathetic in origin.

You can use the classic memory aid Point and Shoot to remember this. Erection, or pointing, receives parasympathetic innervation, while ejaculation (including contraction of the smooth muscle of the seminal vesicles) receives sympathetic innervation.


Lymphatic Drainage

The lymphatic drainage of the gland is the external and internal iliac lymph nodes.

Clinical Relevance

Fig 1.1 - Secretions of the seminal vesicles can be used for the diagnosis of infection by the gram -'ve bacterium Neisseria Gonorrhoeae

Fig 1.1 – Secretions of the seminal vesicles can be used for the diagnosis of infection by the gram -‘ve bacterium Neisseria gonorrhoae

Seminal Gland Abscess

Abscess formation in the seminal glands can allow pus to enter the peritoneal cavity in the event of rupture. Swollen glands can be detected through digital rectal examination (DRE).

Examination and Investigation

The seminal glands can be felt most easily through DRE, especially when the bladder is almost at full capacity. This palpability can allow the glands to be massaged to release their secretions, which can be collected and used for the microscopy of certain STIs such as gonnorhoea.

 

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Question 1 / 3
What structure is located immediately anteriorly to the seminal vesicles?

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What is the innervation of the seminal vesicles?

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How does semen volume change post bilateral vasectomy?

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