The female gonads are called the ovaries. In this article, we will initially look at the basic function, location, components and clinical significance of the ovaries. The latter part of the article will cover the ligaments associated with the ovaries and their vasculature, lymphatic drainage and innervation.
In both the males and females, the gonads develop within the mesonephric ridge and descend through the abdomen. However, unlike the testes, the ovaries stop in the pelvis.
The ovaries are paired, oval organs attached to the posterior surface of the broad ligament of the uterus by the mesovarium (a fold of peritoneum, continuous with the outer surface of the ovaries).
Neurovascular structures enter the hilum of the ovary via the mesovarium.
The main functions of the ovaries are:
1. To produce oocytes (female gametes) in preparation for fertilization.
2. To produce the sex steroid hormones oestrogen and progesterone, in response to pituitary gonadotrophins (LH and FSH).
Components of the Ovary
The ovary has 3 components;
- Surface: The surface layer of the ovary is formed by simple cuboidal epithelium, known as germinal epithelium.
- Cortex: The cortex (outer part) of the ovary is largely comprised of a connective tissue stroma. It supports thousands of follicles. Each primordial follicle contains an oocyte surrounded by a single layer of follicular cells.
- Medulla: The medulla (inner part) is composed of supporting stroma and contains a rich neurovascular network which enters the hilum of ovary from the mesovarium.
Clinical Relevance: Disorders of the Ovaries
Ovarian cysts are fluid-filled masses that may develop in the ovary. They are most commonly derived from ovarian follicles, reaching approximately 2-2.5 cm. Most ovarian cysts are benign and develop during a womans’ child-bearing years, however, some larger cysts may cause problems such as bleeding and pain and require surgical removal.
Polycystic ovaries are characterized by hormone dysfunction and multiple (over 10) ovarian cysts. It is associated with infertility.
Ovarian tumours are another serious disorder. The most common cancers arise from epithelial components or germ cells. 90% of ovarian cancers are derived from epithelium, these are termed ovarian adenocarcinomas, Most germ cell tumours are teratomas, which comprise cells from all 3 germ cell layers and are usually benign.
Two peritoneal ligaments attach to the ovary;
- Suspensory ligament of ovary: fold of peritoneum extending from the mesovarium to the pelvic wall. Contains neurovascular structures.
- Ligament of ovary: extends from the ovary to the fundus of the uterus. It then continues from the uterus to the connective tissue of the labium majus, as the round ligament of uterus.
Vascular Supply and Lymphatics
The ovaries receive blood from paired ovarian arteries, which arise directly from the abdominal aorta, below the renal artery.
Venous drainage is achieved by a pair of ovarian veins. The left ovarian vein drains into the left renal vein, and the right ovarian vein drains directly into the inferior vena cava.
Lymph from the ovaries drains into the para-aortic nodes.
Innervation of the Ovaries
The nerve supply to ovaries runs via the suspensory ligament of the ovary with the vasculature, to enter the ovary at the hilum.
The ovaries receive sympathetic and parasympathetic nerve fibres from the ovarian and uterine (pelvic) plexuses, respectively.